No Association between 5-HTTLPR and Harm Avoidance in Korean College Students.
10.3346/jkms.2007.22.1.138
- Author:
Yeon Ho JOO
1
;
Heung Bum OH
;
Byungsu KIM
;
Suk Hoon JUNG
;
Jun Kyu CHUNG
;
Jin Pyo HONG
;
Chang Yoon KIM
Author Information
1. Department of Psychiatry, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. cykim@amc.seoul.kr
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Anxiety-related personality trait;
5-HTTLPR;
Temperament and Character Inventory;
Harm Avoidance;
Korea;
SLC6A4 protein, human;
Polymorphism, Gentic
- MeSH:
Temperament;
Serotonin Plasma Membrane Transport Proteins/*genetics;
Personality;
Male;
Humans;
*Harm Reduction;
Genotype;
Female;
Exploratory Behavior;
Adult
- From:Journal of Korean Medical Science
2007;22(1):138-141
- CountryRepublic of Korea
- Language:English
-
Abstract:
There have been numerous studies on the association between 5-HTTLPR (polymorphisms in the promoter region of the serotonin transporter gene) and anxietyrelated personality traits, with conflicting results. In this study, we administered Korean version of the Temperament and Character Inventory (K-TCI) to a sample of 158 Korean college students and genotyped for the 5-HTTLPR in order to compare the TCI dimensional scores including harm avoidance according to the 5-HTTLPR genotype and sex. We could not find the association between 5-HTTLPR and harm avoidance and other TCI measures. Considering known allele frequencies differences of 5-HTTLPR among different ethnic groups, further cross-cultural studies with a larger sample would be needed.
