Mechanism of Actions and Clinical Applications of Proton Pump Inhibitors.
- Author:
Sang Yong SEOL
1
Author Information
1. Department of Internal Medicine, Inje University Busan Paik Hospital, Busan, Korea. seolsymd@hanmail.net
- Publication Type:Review ; English Abstract
- Keywords:
Proton pump inhibitors;
Action mechanism;
Clinical application;
Acid-related diseases
- MeSH:
Gastric Acid/*secretion;
Gastrointestinal Agents/pharmacokinetics/*pharmacology/therapeutic use;
Humans;
Proton Pumps/*antagonists & inhibitors
- From:The Korean Journal of Gastroenterology
2006;48(1):4-8
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Proton pump inhibitors (PPIs) are widely used in clinical practice from early 1990s for the treatment of acid- related diseases. PPIs are superior to histamine2-receptor antagonists or anticholinergic agents. These drugs have proven to be effective, safe and well-tolerated during the past two decades. This brief review presents the pharmacodynamics and pharmacokinetics of PPIs and presents clincal applications of the drugs in acid-related diseases.
