Cytogenetic Studies of the Leukocytes of Couples with Habitual Abortions.

Author: Sahsook HAHN ¹ ; Dong Sik KIM
Author Information

1. Department of Pathology, Yonsei University, College of Medicine, Seoul, Korea.
Publication Type:Original Article ; Research Support, Non-U.S. Gov't
Keywords: Cytogenetic study; Habitual abortions
MeSH: Abortion, Habitual/genetics*; Adult; Chromosome Aberrations*; Female; Human; Leukocytes/ultrastructure; Male; Mosaicism; Pregnancy; Translocation (Genetics)
From:Yonsei Medical Journal 1981;22(2):59-70
CountryRepublic of Korea
Language:English
Abstract: Karyotypes were prepared from peripheral blood leukocytes in 18 couples with his-tories of habitual abortions. The Standard chromosome analysis and G-banding techniques were studied. The abnormal karyotypes seen were one case with 20% of 45, XX, -14, -15, t(14/15), one case of 46, XY/45, XY, -21 mosaicism, one case of 45, XX, -14, -21, t(14/21), one case of 46, XX/45, XO mosaicism and one case of 46, XYq+. Many other types of chromosomal abnormalities from many reports in couples with spontaneous abortions are discussed.