Two Cases of Refractory Pseudomembranous Colitis that Healed Following Fecal Microbiota Transplantation.
10.3904/kjm.2013.84.3.395
- Author:
Tae Geun GWEON
1
;
Myung Gyu CHOI
;
Soon Kyu LEE
;
Jeong Hoon HA
;
Eun Young KIM
;
Byoung Soung GO
;
Sang Woo KIM
Author Information
1. Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. viper@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
C. difficile infection;
Pseudomembranous colitis;
Fecal microbiota transplantation
- MeSH:
Clostridium difficile;
Enterocolitis, Pseudomembranous;
Humans;
Incidence;
Metagenome;
Metronidazole;
Recurrence;
Transplants;
Treatment Failure;
Vancomycin
- From:Korean Journal of Medicine
2013;84(3):395-399
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The incidence, recurrence, and mortality of Clostridium difficile infection are increasing and the standard therapy is oral metronidazole or vancomycin. Since treatment failure with standard therapy is increasing, an alternative therapy is needed. Fecal microbiota transplantation is one effective method in patients with refractory or recurrent C. difficile infection, including pseudomembranous colitis. Here, we report two cases of refractory pseudomembranous colitis treated with fecal microbiota transplantation.
