Antibacterial effects of carvacrol against Staphylococcus aureus and Escherichia coli O157:H7.
10.12729/jbr.2014.15.3.117
- Author:
Youyoung CHO
1
;
Hu Jang LEE
Author Information
1. Department of Nursing, Hanyeong College, Yeosu 550-704, Korea.
- Publication Type:Original Article
- Keywords:
foodborne disease;
carvacrol;
antibacterial activity;
Staphylococcus aureus;
Escherichia coli O157:H7
- MeSH:
Escherichia coli*;
Foodborne Diseases;
Kinetics;
Microbial Sensitivity Tests;
Milk;
Staphylococcus aureus*
- From:Journal of Biomedical Research
2014;15(3):117-122
- CountryRepublic of Korea
- Language:English
-
Abstract:
The objective of this study was to investigate the antimicrobial effects of carvacrol (CV) against Staphylococcus aureus (S. aureus) and Escherichia coli O157:H7 (E. coli O157:H7) strains in milk. The minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) of CV against S. aureus and E. coli O157:H7 were determined. In addition, bactericidal kinetics and antimicrobial activity of CV against the aforementioned pathogens in milk over a period of 2 weeks were investigated. CV exhibited antibacterial activity against both foodborne pathogens tested. The MIC and MBC of CV against S. aureus were 15.0 and 20 mg/mL, respectively, whereas those against E. coli O157:H7 were 16.0 and 32 mg/mL, respectively. In time-kill assays, CV at MBC reduced the number of S. aureus and E. coli O157:H7 in milk to undetectable levels within 24 hr. The antibacterial effects of CV persisted for 14 days without any loss of activity. Results of this study suggest that CV has a potential antibacterial activity against foodborne pathogens such as S. aureus and E. coli O157:H7 in milk.
