Screening and Identifying Erosive Esophagitis in Children with Non-cardiac Chest Pain.
10.3346/jkms.2016.31.2.270
- Author:
Hye Won PARK
1
;
You Jin CHOI
;
Su Jin JEONG
Author Information
1. Department of Pediatrics, CHA Bundang Medical Center, CHA University, Seongnam, Korea. jinped@cha.ac.kr
- Publication Type:Original Article
- Keywords:
Chest Pain;
Erosive Esophagitis;
Gastroesophageal Reflux;
Diet;
Pediatrics
- MeSH:
Adolescent;
Chest Pain;
Child;
Child, Preschool;
Demography;
Endoscopy, Digestive System;
Esophagitis/*diagnosis;
Female;
Gastroesophageal Reflux/diagnosis;
Humans;
Male;
Odds Ratio;
Retrospective Studies;
Risk Factors;
Sleep;
Surveys and Questionnaires
- From:Journal of Korean Medical Science
2016;31(2):270-274
- CountryRepublic of Korea
- Language:English
-
Abstract:
Non-cardiac chest pain is a common disorder that leads to costly evaluations to distinguish it from cardiac pain. The present study aimed to clarify the clinical characteristics of erosive esophagitis in children with non-cardiac chest pain. Ninety nine patients (mean age, 9.55 ± 2.95 years, 49 girls) with non-cardiac chest pain were enrolled. Patients were classified into two groups: erosive esophagitis and non-erosive esophagitis-related non-cardiac chest pain by esophagogastroduodenoscopy. Children in the erosive esophagitis-related non-cardiac chest pain group were significantly older (10.95 ± 2.54 years vs. 8.52 ± 2.83 years). Multivariate logistic regression analysis identified the following predictors of gastroesophageal reflux: chest pain related to sleep (odds ratio = 18.05, 95% confidence interval: 3.18-102.49); unfavorable dietary habits (odds ratio = 7.11, 95% confidence interval: 1.53-32.87); chest pain related to food (odds ratio = 5.09, 95% confidence interval: 1.37-18.86); epigastric pain (odds ratio = 3.73, 95% confidence interval: 1.12-12.33); and nausea, vomiting, and/or regurgitation (odds ratio = 4.35, 95% confidence interval: 1.22-15.54). Gastroesophageal reflux disease should be considered first in children with non-cardiac chest pain. Children with gastroesophageal reflux disease should receive medical treatment and lifestyle modifications.