Solitary Hemangioblastoma at the Filum Terminale: A Case Report and Review of Literature.
10.14245/kjs.2011.8.2.125
- Author:
Jung Hoon LEE
1
;
Jin Uk KIM
;
Sung Suk PAENG
;
Jee Soo JANG
;
Sang Ho LEE
Author Information
1. Department of Neurosurgery, Seoul Wooridul Hospital, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Spinal hemangioblastoma;
Filum terminale;
Immunohistopathological stain
- MeSH:
Cauda Equina;
Coloring Agents;
Decompression;
Endothelial Cells;
Female;
Hemangioblastoma;
Humans;
Hypesthesia;
Low Back Pain;
Lower Extremity;
Middle Aged;
Phosphopyruvate Hydratase;
Stromal Cells;
von Willebrand Factor
- From:Korean Journal of Spine
2011;8(2):125-128
- CountryRepublic of Korea
- Language:English
-
Abstract:
Spinal hemangioblastomas at the filum terminale are rare. Only a few reports present immunohistopathological features of spinal hemangioblastomas. A 55-year-old woman presented with sustained low back pain and intermittent numbness in both lower extremities. She already had a decompressive surgery for a left L5-S1 extraforaminal lesion 7 months ago. Her incidental mass lesion had been slightly enlarged for 7 months and concordant symptoms had also been prolonged. Her tumor was removed en bloc with a unilateral hemilaminotomy and bilateral decompression technique. The patient's symptoms improved immediately after the surgery. In immunohistochemical stains, the stromal cells were positive for inhibin-alpha, neuron specific enolase (NSE), and the endothelial cells were positive for CD31, CD34, and factor VIII related antigen in confirming the diagnosis of hemangioblastoma. We report a rare case of intradural extramedullary spinal hemangioblastoma at the filum terminale. Complete en bloc resection was achieved with no morbidity. The immunohistopathological staining include inhibin-alpha confirmed an accurate diagnosis of the hemangioblastoma distinguishing from other vascular tumors.
