Retinal Detachment with Macular Hole Following Combined Photodynamic Therapy and Intravitreal Bevacizumab Injection.
10.3341/kjo.2007.21.3.185
- Author:
Eun Jee CHUNG
1
;
Hyoung Jun KOH
Author Information
1. The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea. hjkoh@yuns.ac.kr
- Publication Type:Case Report
- Keywords:
Intravitreal bevacizumab injection;
Macular hole detachment;
Photodynamic therapy
- MeSH:
Angiogenesis Inhibitors/administration & dosage/*adverse effects/therapeutic use;
Antibodies, Monoclonal/administration & dosage/*adverse effects/therapeutic use;
Choroidal Neovascularization/*drug therapy;
Female;
Humans;
Injections;
Middle Aged;
Photochemotherapy/*adverse effects;
Retinal Detachment/*etiology;
Retinal Perforations/*etiology;
Vitreous Body
- From:Korean Journal of Ophthalmology
2007;21(3):185-187
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To report a case of retinal detachment with a macular hole following photodynamic therapy (PDT) using verteporfin and intravtreal bevacizumab injection in the treatment of myopic choroidal neovasclarization (CNV). METHODS: A 58 -year-old woman was diagnosed with myopic CNV and treated with a combination of PDT with verteporfin and intravitreal bevacizumab injection that same day. She received the second injection of intravitreal bevacizumab four weeks after the initial treatment. RESULTS: The patient developed a sudden decline in vision one week after the second injection; and was subsequently diagnosed with retinal detachment associated with a macular hole. She underwent standard three-port pars plana vitrectomy with internal limiting membrane peeling, fluid-air exchange and silicone oil injection. The retina was still firmly attached at the patient's final follow-up visit. CONCLUSIONS: PDT and intravitreal bevacizumab injection used for the treatment of myopic CNV can be associated with retinal detachment with a macular hole. Patients need to be informed about this potential complication, and a higher index of suspicion may be warranted in patients who report sudden vision loss after the treatment.
