Two Cases of Acute Renal Failure Complicating Paroxysmal Nocturnal Hemoglobinuria in Children.
- Author:
Jung Min RYU
1
;
Yohan AHN
;
Sohee LEE
;
Hyun Jin CHOI
;
Beom Hee LEE
;
Hee Gyung KANG
;
Hyoung Jin KANG
;
Hee Young SHIN
;
Il Soo HA
;
Hae Il CHEONG
;
Hyo Seop AHN
;
Yong CHOI
Author Information
1. Department of Pediatrics, Seoul National University Childrens Hospital, Seoul, Korea. ilsooha@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Paroxysmal nocturnal hemoglobinuria(PNH);
Acute renal failure;
Intravascular hemolysis;
Children
- MeSH:
Acute Kidney Injury;
Bone Marrow;
Child;
Diagnosis, Differential;
Hemoglobinuria;
Hemoglobinuria, Paroxysmal;
Hemolysis;
Humans
- From:Journal of the Korean Society of Pediatric Nephrology
2008;12(2):221-226
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Paroxysmal nocturnal hemoglobinuria(PNH) is an acquired hematologic disorder characterized by intravascular hemolysis, nocturnal hemoglobinuria, thrombotic events and bone marrow failure. It rarely occurs in children and can be complicated by acute renal failure(ARF). Here, we present two cases of ARF complicating PNH which has not been reported yet in Korean children. We suggest that PNH should be considered in differential diagnosis of ARF in children associated with intravascular hemolysis.
