Diagnosis of Systemic Lupus Erythematosus During Medical Follow-up After Urinary Screening.
- Author:
So Jin YOON
1
;
Ji Eun SONG
;
Jae Il SHIN
;
Il Cheon JEONG
;
Jae Seung LEE
;
Hyo Sup SHIM
;
Hyeon Joo JEONG
Author Information
1. The Institute of Kidney Disease, Yonsei University College of Medicine, Severance Childrens Hospital, Seoul, Korea. jsyonse@yuhs.ac
- Publication Type:Case Report
- Keywords:
Systemic lupus erythematosus(SLE);
Lupus nephritis(LN)
- MeSH:
Adolescent;
Biopsy;
Cyclophosphamide;
Erythema;
Follow-Up Studies;
Glomerulonephritis;
Hematuria;
Humans;
Lupus Erythematosus, Systemic;
Lupus Nephritis;
Lymphadenitis;
Mass Screening;
Neck;
Peptidyl-Dipeptidase A;
Pregnenediones;
Proteinuria;
Thrombocytopenia
- From:Journal of the Korean Society of Pediatric Nephrology
2008;12(2):227-232
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 16-year-old girl presented with proteinuria and microscopic hematuria detected through mass urinary screening and was diagnosed as having suspected postinfectious glomerulonephritis by renal biopsy. However, heavy proteinuria did not respond to angiotensin converting enzyme inhibitor therapy. After 6 months, cervical lymphadenitis developed and a neck node biopsy showed subacute necrotizing lymphadenitis. After an additional 2 months, she developed facial erythema and thrombocytopenia. A repeat renal biopsy demonstrated lupus nephritis class IV. She was treated with pulse methylprednisolone(500 mg/day intravenously for 3 consecutive days) followed by oral deflazacort and monthly intravenous cyclophosphamide pulse(1 g/m2) for 6 months. We report a case diagnosed as systemic lupus erythematosus(SLE) during medical follow-up after urinary screening.
