Photodynamic Therapy with Vertepofin for Short Time for Chronic Central Serous Chorioretinopathy.
10.3341/jkos.2008.49.7.1078
- Author:
Jung Lim KIM
1
;
Hyun Woong KIM
;
Il Han YOON
Author Information
1. Department of Ophthalmology, College of Medicine, Inje University, Pusan, Korea.
- Publication Type:Original Article
- Keywords:
Chronic central serous chorioretinopathy;
Indocyanine green angiography;
Optical coherence tomography;
Photodynamic therapy
- MeSH:
Central Serous Chorioretinopathy;
Eye;
Fluorescein;
Follow-Up Studies;
Humans;
Photochemotherapy;
Porphyrins;
Recurrence;
Retrospective Studies;
Tomography, Optical Coherence;
Triazenes;
Vision, Ocular;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2008;49(7):1078-1086
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the clinical results of short duration photodynamic therapy (PDT) using verteporfin in patients with chronic central serous chorioretinopathy (CSC). METHODS: We retrospectively examined 15 eyes after PDT for chronic central serous chorioretinopathy. PDT for 83 seconds was evaluated for 8 eyes, and PDT for 60 seconds was evaluated for 7 eyes. Improvement in vision and changes in central macular thickness were evaluated with an optical coherence tomogram (OCT), and improvement in leaking was evaluated with a fluorescein angiogram (FA). Recurrence was also studied. RESULTS: Visual acuity improved from 0.39 to 0.57 (p=0.04), and the mean central macular thickness decreased from 426.29 micrometer to 184.71 micrometer (p<0.01) in 7 eyes treated with PDT for 60 seconds. There was no significant change in visual acuity between the two groups (p=0.77) or in central macular thickness (p=0.52). Central macular exudation resolved completely in all eyes. After PDT, there was no recurrence during the follow-up period. CONCLUSIONS: Short duration PDT with verteporfin appears to be a beneficial treatment option for patients with chronic CSC.
