Menetrier's Disease: Its Mimickers and Pathogenesis.
- Author:
Won Jae HUH
1
;
Robert J COFFEY
;
Mary Kay WASHINGTON
Author Information
- Publication Type:Review
- Keywords: Menetrier's disease; Gastric polyp; Transforming growth factor alpha
- MeSH: Gastritis, Hypertrophic*; Receptor, Epidermal Growth Factor; Transforming Growth Factor alpha
- From:Journal of Pathology and Translational Medicine 2016;50(1):10-16
- CountryRepublic of Korea
- Language:English
- Abstract: Menetrier's disease is a rare protein-losing hypertrophic gastropathy. Histologically, it can be mistaken for other disorders showing hypertrophic gastropathy. The pathogenesis of Menetrier's disease is not fully understood; however, it appears that the epidermal growth factor receptor (EGFR) ligand, transforming growth factor alpha, contributes to the pathogenesis of this disorder. In this review, we will discuss disease entities that can mimic Menetrier's disease and the role of EGFR signaling in Menetrier's disease.
