Clinical Usefulness of Dopamine Transporter Imaging.
- Author:
Jong Min KIM
1
;
Yu Kyeong KIM
;
Sang Eun KIM
;
Beom S JEON
Author Information
1. Department of Neurology, Seoul National University College of Medicine, MRC and BK-21, Clinical Research Institute, Seoul National University Hospital and Bundang Hospital, Seoul, Korea. brain@snu.ac.kr
- Publication Type:Review
- Keywords:
dopamine transporter;
parkinsonism;
Parkinson disease
- MeSH:
Diagnosis;
Diagnosis, Differential;
Dopamine Plasma Membrane Transport Proteins*;
Dopamine*;
Essential Tremor;
Humans;
Multiple System Atrophy;
Parkinson Disease;
Parkinsonian Disorders;
Supranuclear Palsy, Progressive
- From:Nuclear Medicine and Molecular Imaging
2007;41(2):152-157
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Imaging of the dopamine transporter (DAT) provides a marker for the integrity of presynaptic nigrostriatal dopaminergic system. DAT density is reduced in Parkinson disease, multiple system atrophy, and progressive supranuclear palsy. In patients with suspicious parkinsonism, normal DAT imaging suggests an alternative diagnosis such as essential tremor, vascular parkinsonism, or drug-induced parkinsonism. DAT imaging is a useful tool to aid clinician's differential diagnosis in parkinsonism.
