A Case of Woringer-Kolopp Disease on the Leg.
- Author:
Sang Hoon PARK
1
;
Tae Woo NOH
;
Kwang Cheol HONG
;
Yoo Seok KANG
;
Un Ha LEE
;
Hyun Su PARK
;
Sang Jai JANG
Author Information
1. Department of Dermatology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea. woods75@hanmail.net
- Publication Type:Case Report
- Keywords:
Cutaneous lymphoma;
Pagetoid reticulosis;
Woringer-Kolopp disease
- MeSH:
Biopsy;
Epidermis;
Extremities;
Female;
Humans;
Leg;
Middle Aged;
Mycosis Fungoides;
Pagetoid Reticulosis;
Phenotype;
Skin
- From:Korean Journal of Dermatology
2010;48(11):1020-1023
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Woringer-Kolopp disease is a rare variant of mycosis fungoides and it is also known as localized pagetoid reticulosis. It presents as a solitary, localized hyperkeratotic patch or plaque on the extremities with a slowly progressive course. A 51-year-old female presented with a 6-year history of a well-defined erythematous plaque with an indurate border on the left leg. The lesion was asymptomatic and it had gradually enlarged. A skin biopsy showed hyperkeratosis and acanthotic epidermis with an infiltration of atypical pagetoid cells, and these cells were revealed to be the cytotoxic T cell phenotype on immunohistochemical staining. We report here on a case of Woringer-Kolopp disease along with a review of the relevant literature.
