A Case of Ki-1 Positive Type B Lymphomatoid Papulosis.
- Author:
Min Ja JUNG
;
Sang Jun LEE
;
Yoon Whoa CHO
;
Jee Yoon HAN
;
Kye Yong SONG
- Publication Type:Case Report
- MeSH:
B-Lymphocytes;
Cicatrix;
Hodgkin Disease;
Hyperpigmentation;
Lymphocytes;
Lymphoma;
Lymphomatoid Papulosis*;
Mycosis Fungoides;
Reed-Sternberg Cells;
T-Lymphocytes
- From:Korean Journal of Dermatology
1998;36(3):540-544
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The monoclonal antibody Ki-1(CD30) was first described in 1982 and was reported to react selectively with Reed-Sternberg cells in Hodgkins disease, highly activated B and T cells and large cell lymphomas of both T-and B-cell origin. Lymphomatoid papulosis(LyP) is characterized by recurrent erythematous papules or nodules that undergo spontaneous healing with hyperpigmentation and scarring. Histologically, two major types of LyP can be distinguished: type A is characterized by the presence of variable numbers of Ki-1+ large, atypical lymphocytes with some Reed-Sternberg like cells and type B is characterized by Ki-1- atypical cerebriform mononuclear cells similar to those in mycosis fungoides. We report a case of Ki-1+ lymphomatoid papulosis which was histopathologically recognized as a type B lesion but represented a Ki-1 positive reaction.
