Endometrial Stromal Sarcoma Presented as an Incidental Lung Mass with Multiple Pulmonary Nodules.
10.4046/trd.2014.76.3.131
- Author:
Dong Oh KANG
1
;
Sue In CHOI
;
Jee Youn OH
;
Jae Kyeom SIM
;
Jong Hyun CHOI
;
Ji Yung CHOO
;
Jin Wook HWANG
;
Seung Heon LEE
;
Ju Han LEE
;
Ki Yeol LEE
;
Chol SHIN
;
Je Hyeong KIM
Author Information
1. Division of Pulmonology, Sleep and Critical Care Medicine, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea. chepraxis@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Sarcoma, Endometrial Stromal;
Multiple Pulmonary Nodules;
Neoplasm Metastasis
- MeSH:
Adult;
Biopsy;
Diagnosis;
Diagnostic Errors;
Female;
Humans;
Leiomyoma;
Lung*;
Mesoderm;
Multiple Pulmonary Nodules*;
Neoplasm Metastasis;
Progesterone;
Sarcoma, Endometrial Stromal*;
Uterine Myomectomy;
Uterine Neoplasms
- From:Tuberculosis and Respiratory Diseases
2014;76(3):131-135
- CountryRepublic of Korea
- Language:English
-
Abstract:
Low-grade endometrial stromal sarcoma (ESS) is an uncommon gynecologic malignancy of mesodermal origin. Pulmonary metastasis of low-grade ESS can occur years and decades after the treatment of the primary disease. Low-grade ESS is frequently mistaken as benign uterine neoplasm like uterine leiomyoma, which can potentially lead to a misdiagnosis. We present a case of a 42-year-old woman with low-grade ESS, that initially presented as an incidental lung mass with multiple pulmonary nodules, seven years after an uterine myomectomy. A 6.9x5.8 cm-sized intrapelvic mass suspected of uterine origin was discovered while searching for potential extrathoracic primary origin. A pelviscopy and simultaneous thoracoscopic lung biopsy were conducted for pathologic diagnosis. Finally, the diagnosis was confirmed as low-grade ESS with lung metastasis based on the histopathologic examination with immunohistochemical stain, which was showed positive for CD10 and hormone receptor markers (estrogen and progesterone receptors) in both pelvic and lung specimens.
