Effect of early enteral nutrition after hepatectomy in hepatocellular carcinoma patients.
10.14701/kjhbps.2012.16.4.129
- Author:
Jonghwan LEE
1
;
Choon Hyuck David KWON
;
Jong Man KIM
;
Milljae SHIN
;
Jae Won JOH
Author Information
1. Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. chdkwon@skku.edu
- Publication Type:Original Article
- Keywords:
Early recovery after surgery;
Early diet;
Gastrointestinal motility;
Liver function;
Postoperative admission days
- MeSH:
Alanine Transaminase;
Aspartate Aminotransferases;
Bilirubin;
C-Reactive Protein;
Carcinoma, Hepatocellular;
Diet;
Enteral Nutrition;
Gastrointestinal Motility;
Hepatectomy;
Humans;
International Normalized Ratio;
Leukocytes;
Liver;
Nausea;
Postoperative Complications;
Prothrombin Time;
Recovery of Function;
Vomiting;
Water
- From:Korean Journal of Hepato-Biliary-Pancreatic Surgery
2012;16(4):129-133
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUNDS/AIMS: To evaluate the effect of early enteral nutrition after hepatectomy in hepatocellular carcinoma (HCC) patients on postoperative gastrointestinal motility recovery and admission days, liver function and nutrition recovery, and postoperative complication. METHODS: From August 2010 to July 2011, 102 patients with primary HCC underwent hepatectomy. Forty two patients took a sip of water (SOW) at postoperative day (POD)#1, soft blended diet (SBD) at POD#2 (early diet group, ED group), otherwise 60 patients took a SOW at POD#3, SBD at POD#4 (conventional diet group, CD group). Postoperative flatus-pass day, stool-pass day, nausea, vomiting, admission days, immediate postoperative (POD#0) and POD#1, 3, 5, 7 profiles of albumin, prothrombin time (PT) INR, total bilirubin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), white blood cell (WBC), and POD#1, 3, 5, 7 profiles of C-reactive protein (CRP), and postoperative complications cases were compared between ED group and CD group. All clinical data were compared retrospectively. RESULTS: Flatus-pass days (p<0.01), stool-pass days (p<0.01) and postoperative admission days (p=0.012) were shorter in ED group. Total bilirubin levels were higher at POD#0, 1, 3 but lower or similar at POD#5, 7 in ED group. AST, ALT levels were higher at POD#0 but lower at POD#1, 3, 5. There were no significant differences in albumin, PT INR, WBC, CRP and postoperative complication rates. CONCLUSIONS: ED group had no difference in nutritional recovery and postoperative complication rates compared to CD group but it has better gastrointestinal motility recovery, liver function recovery, and shorter postoperative admission days.
