Clinical Features of Kawasaki Disease with Pyuria.
10.14776/piv.2017.24.3.141
- Author:
Hyo Jin KIM
1
;
Joo Young LEE
;
Ui Yoon CHOI
;
Soo Young LEE
Author Information
1. Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, the Republic of Korea. sylee@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Mucocutaneous lymph node syndrome;
Pyuria;
Fever;
Child
- MeSH:
Anti-Bacterial Agents;
C-Reactive Protein;
Child;
Coronary Vessels;
Fever;
Humans;
Immunoglobulins;
Inflammation;
Inpatients;
Liver;
Male;
Medical Records;
Mucocutaneous Lymph Node Syndrome*;
Pyuria*;
Retrospective Studies;
Urinary Tract Infections
- From:Pediatric Infection & Vaccine
2017;24(3):141-145
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Clinical and laboratory features of two Kawasaki disease (KD) groups were evaluated; the patient with pyuria and those without pyuria. METHODS: From January 2015 to December 2016, the medical records of 140 (86 males and 54 females) inpatients with KD were retrospectively analyzed. RESULTS: Forty-eight KD patients (34.3%) presented with pyuria. KD patients with pyuria showed a higher level of C-reactive protein (CRP) and a higher proportion of elevated liver enzymes than those without pyuria. There were no differences in the proportions of unresponsiveness to intravenous immunoglobulin and coronary artery lesions between the two groups. Six KD patients (12.5%) with pyuria underwent a renal imaging study to rule out the possibility of a urinary tract infections. Thirty-two KD patients (66.7%) with pyuria received treatment with antibiotics in addition to the standard treatment for KD. CONCLUSIONS: KD patients with pyuria showed a higher level of CRP and elevated levels of liver enzymes than those without pyuria. These findings suggest that KD patients with pyuria have more severe systemic inflammation than those without pyuria.