Non-familial Acrokeratosis Verruciformis of Hopf.
10.5021/ad.2011.23.S1.S61
- Author:
Chul Hwan BANG
1
;
Hei Sung KIM
;
Young Min PARK
;
Hyung Ok KIM
;
Jun Young LEE
Author Information
1. Department of Dermatology, The Catholic University of Korea School of Medicine, Seoul, Korea. jylee@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Acrokeratosis verruciformis of Hopf;
Non-familial acrokeratosis verruciformis
- MeSH:
Adult;
Darier Disease;
Foot;
Hand;
Humans;
Keratins;
Papilloma;
Parturition;
Skin;
Warts;
Wills
- From:Annals of Dermatology
2011;23(Suppl 1):S61-S63
- CountryRepublic of Korea
- Language:English
-
Abstract:
Acrokeratosis verruciformis of Hopf is a rare genodermatosis with an autosomal dominant mode of inheritance. It is a disorder of keratinization, characterized by multiple, flat-topped, skin-colored keratotic lesions resembling plane warts typically observed on the dorsum of the hands and feet. Histopathologically, the lesion shows considerable hyperkeratosis, acanthosis, and papillomatosis, mimicking a "church spire", and a thickened granular layer. It arises in early life, often at birth or infancy. Herein, we report on a rare sporadic case of acrokeratosis verruciformis of Hopf. A 44-year-old Caucasian man presented with multiple, grouped, hyperkeratotic, whitish, flat papules on his shins and feet, which had been present for more than one year. Histopathological examination showed typical findings of acrokeratosis verruciformis of Hopf. Our case is unique in that the patient had no familial history of similar skin lesions.
