Primary choriocarcinoma of the urinary bladder: a case report.
10.3346/jkms.1992.7.4.369
- Author:
Jeong Hee CHO
1
;
Eun Sil YU
;
Kwang Hoon KIM
;
In Chul LEE
Author Information
1. Department of Pathology, Asan Medical Center College of Medicine, University of Ulsan, Seoul, Korea.
- Publication Type:Case Reports ; Review
- Keywords:
Choriocarcinoma;
Urinary bladder;
Immunohistochemical study
- MeSH:
Choriocarcinoma/*pathology;
Humans;
Male;
Middle Aged;
Urinary Bladder Neoplasms/*pathology
- From:Journal of Korean Medical Science
1992;7(4):369-372
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report a primary choriocarcinoma of the urinary bladder in a 63-year-old man who presented with painless hematuria. He was diagnosed as having an invasive carcinoma and underwent a total cystectomy. The tumor was diffusely hemorrhagic and occupied the dome of the bladder. Histologically, it consisted of cyto-and syncytiotrophoblasts with extensive hemorrhage. No coexisting transitional cell carcinoma component was present. By immunohistochemistry, the tumor expressed beta-hCG and low-molecular weight cytokeratin intensely while it was negative for CEA or EMA. The post-cystectomy serum beta-hCG was 237mlU/ml, and decreased later. The pertinent literature is reviewed and diagnostic criteria are discussed.