A family case of beta-thalassemia minor and hemoglobin Queens: alpha 34 (B15) Leu-Arg.
10.3346/jkms.1992.7.4.385
- Author:
Nam Yong LEE
1
;
Han Ik CHO
;
Sang In KIM
;
Byoung Kook KIM
;
Yuzo OHBA
;
Yukio HATTORI
Author Information
1. Department of Clinical Pathology, Seoul National University College of Medicine, Korea.
- Publication Type:Case Reports
- Keywords:
beta-thalassemia minor;
Hb Queens
- MeSH:
Adult;
Arginine/genetics;
Female;
Hemoglobins, Abnormal/*genetics;
Humans;
Korea;
Leucine/genetics;
Male;
Pedigree;
beta-Thalassemia/blood/*genetics
- From:Journal of Korean Medical Science
1992;7(4):385-388
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report a Korean family case of beta-thalassemia minor and Hb Queens. This is the first case report of Hb Queens in Korea. A 43-year-old male and his four family members had beta-thalassemia minor which is very rare in Korea. Incidentally, an alpha chain variant with a high isoelectric point was also found in two other family members without clinical problems and was finally identified as alpha 34 (B15) Leu-Arg or Hemoglobin Queens.
