Recurrent Deep Vein Thrombosis due to Thrombophilia.
10.4070/kcj.2012.42.5.345
- Author:
Afzalur RAHMAN
1
;
AKM Monwarul ISLAM
;
SAM HUSNAYEN
Author Information
1. Department of Cardiology, Sir Salimullah Medical College & Mitford Hospital, Dhaka, Bangladesh.
- Publication Type:Case Report
- Keywords:
Deep vein thrombosis;
Thrombophilia
- MeSH:
Heparin;
Humans;
Protein C;
Protein S;
Protein S Deficiency;
Thrombophilia;
Venous Thromboembolism;
Venous Thrombosis;
Warfarin
- From:Korean Circulation Journal
2012;42(5):345-348
- CountryRepublic of Korea
- Language:English
-
Abstract:
Deep vein thrombosis (DVT) is a common condition that is often under-diagnosed. Acquired or hereditary defects of coagulation or a combination of these defects may facilitate the development of DVT. Recurrent DVT, a positive family history or unusual presentation may warrant investigation for hereditary thrombophilia. Investigations are best when conducted at least one month after completion of a course of anticoagulant therapy. Most patients are managed with heparin in the acute stage overlapped by warfarin. The case presented here describes a 40-year old man undergoing three episodes of DVT. Investigations revealed protein C and protein S deficiency. Protein C, protein S and antithrombin deficiency either singly or in combination, are relatively common causes of hereditary thrombophilia. The case presented here serves as a reminder of the need to look into the underlying cause of venous thromboembolism.
