Radiolabeling Methods Used for Preparation of Molecular Probes.
- Author:
Yearn Seong CHOE
1
Author Information
1. Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. yschoe@samsung.co.kr
- Publication Type:Original Article
- Keywords:
Molecular probe;
Radioisotope;
Radiolabeling method;
Small organic molecules;
Proteins;
Peptides;
PET;
SPECT
- MeSH:
Molecular Imaging;
Molecular Probes*;
Peptides;
Radioisotopes;
Tomography, Emission-Computed, Single-Photon
- From:Korean Journal of Nuclear Medicine
2004;38(2):121-130
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Molecular imaging visualizes cellular processes at a molecular or genetic level in living subjects, and diverse molecular probes are used for this purpose. Radiolabeling methods as well as radioisotopes are very important in preparation of molecular probes, because they can affect the biodistribution in tissues and the excretion route. In this review, the molecular probes are divided into small organic molecules and macromolecules such as peptides and proteins, and their commonly used radiolabeling methods are described.
