Disseminated Mycobacterium intracellulare Infection in an Immunocompetent Host.
10.4046/trd.2012.72.5.452
- Author:
Won Young KIM
1
;
Sun Joo JANG
;
Taejin OK
;
Gwang Un KIM
;
Han Seung PARK
;
Jaechan LEEM
;
Bo Hyoung KANG
;
Se Jeong PARK
;
Dong Kyu OH
;
Byung Ju KANG
;
Bo Young LEE
;
Won Jun JI
;
Tae Sun SHIM
Author Information
1. Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. shimts@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Nontuberculous Mycobacteria;
Immunocompetence;
Positron-Emission Tomography;
Hybridization, Genetic
- MeSH:
Biopsy;
Humans;
Hybridization, Genetic;
Hydrazines;
Immunocompetence;
Immunocompromised Host;
Lung;
Lymph Nodes;
Mycobacterium;
Mycobacterium avium Complex;
Mycobacterium avium-intracellulare Infection;
Neoplasm Metastasis;
Nontuberculous Mycobacteria;
Positron-Emission Tomography;
Spleen
- From:Tuberculosis and Respiratory Diseases
2012;72(5):452-456
- CountryRepublic of Korea
- Language:English
-
Abstract:
Disseminated Mycobacterium avium complex (MAC) infection can occur in immunocompromised patients, and rarely in immunocompetent subjects. Due to the extensive distribution of the disease, clinical presentation of disseminated MAC may mimic malignancies, and thorough examinations are required in order to make accurate diagnosis. We report a case of disseminated Mycobacterium intracellulare disease in an immunocompetent patient, which involved the lung, lymph nodes, spleen, and multiple bones. F-18 fluorodeoxyglucose positron-emission tomography imaging showed multiple hypermetabolic lesions, which are suggestive of typical hematogenous metastasis. However, there was no evidence of malignancy in serial biopsies, and M. intracellulare was repeatedly cultured from respiratory specimens and bones. Herein, we should know that disseminated infection can occur in the immunocompetent subjects, and it can mimic malignancies.
