Naproxen-induced Immune Thrombocytopenia: A case report.
10.3344/kjp.2006.19.2.285
- Author:
Cheol Kun KIM
1
;
In Su JANG
;
Jun Hak LEE
;
Young Eun KWON
;
Sang Chul PARK
Author Information
1. Department of Anesthesiology and Pain Medicine, Presbyterian Medical Center, Jeonju, Korea. kwon8373@yahoo.co.kr
- Publication Type:Case Report
- Keywords:
immune;
naproxen;
thrombocytopenia
- MeSH:
Epistaxis;
Hemorrhage;
Humans;
Immunoglobulins;
Middle Aged;
Naproxen;
Platelet Count;
Thrombocytopenia*
- From:The Korean Journal of Pain
2006;19(2):285-287
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hundreds of drugs have been implicated as the causes of antibody-mediated thrombocytopenia. Naproxen is a commonly used nonsteroidal anti-inflammatory drug, and it is generally considered to be safe with few hematological side effects such as thrombocytopenia. In this case, severe thrombocytopenia associated with petechia and epistaxis appeared after initiation of naproxen therapy in the 59-year-old man. We report here on a case of severe thrombocytopenia that was recognized at 10 days after the use of naproxen, and the patient rapidly recovered to a normal platelet count without bleeding symptoms or any complications, although immunoglobulin or steroid was not used.