A Malignant Transformation of a Spinal Epidural Mass from Ganglioneuroblastoma to Neuroblastoma.
10.3340/jkns.2015.57.3.211
- Author:
Mehmet Osman AKCAKAYA
1
;
Bilge BILGIC
;
Yavuz ARAS
;
Nail IZGI
Author Information
1. Department of Neurosurgery, School of Medicine, Istanbul University, Istanbul, Turkey. moakcakaya@gmail.com
- Publication Type:Case Report
- Keywords:
Ganglioneuroblastoma;
Neuroblastoma;
Malignant transformation;
Spinal tumor
- MeSH:
Disease-Free Survival;
Ganglioneuroblastoma*;
Ganglioneuroma;
Humans;
Neuroblastoma*;
Prognosis
- From:Journal of Korean Neurosurgical Society
2015;57(3):211-214
- CountryRepublic of Korea
- Language:English
-
Abstract:
Ganglioneuromas are benign tumors. Surgical excision is the treatment of choice with very good prognosis. However, neuroblastomatous malignant transformation of ganglioneuromas was previously reported. We report a patient with spinal neuroblastoma recurrent from a ganglioneuroblastoma after disease free survival of 13 years. This is one of the rare examples of spinal neuroblastoma and to our knowledge the second case report with malignant transformation from a ganglioneuroblastoma or a ganglioneuroma. The present case is the only report in the literature with further genetic investigations.
