Relationship between Sarcopenic Obesity and Cardiovascular Disease Risk as Estimated by the Framingham Risk Score.
10.3346/jkms.2015.30.3.264
- Author:
Jeong Hyeon KIM
1
;
Jung Jin CHO
;
Yong Soon PARK
Author Information
1. Department of Family Medicine, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea. pyongs@hanmail.net
- Publication Type:Original Article
- Keywords:
Sarcopenia;
Obesity;
Cardiovascular Diseases;
Risk Assessment;
KNHANES
- MeSH:
Aging;
Body Composition/physiology;
Body Mass Index;
Body Weight;
Cardiovascular Diseases/*epidemiology;
Cross-Sectional Studies;
Diabetes Mellitus/epidemiology;
Female;
Humans;
Male;
Middle Aged;
Muscle, Skeletal/*physiology;
Obesity/*epidemiology;
Risk;
Risk Factors;
Sarcopenia/*epidemiology;
Sex Factors
- From:Journal of Korean Medical Science
2015;30(3):264-271
- CountryRepublic of Korea
- Language:English
-
Abstract:
This study was conducted to assess the association between sarcopenic obesity and cardiovascular disease (CVD) risk in Korean adults (n=3,320; > or =40 yr) who participated in the 5th Korean National Health and Nutrition Examination Survey in 2010. The appendicular skeletal muscle mass divided by body weight was calculated for each participant; participants with values <1 standard deviation below the mean reference value (i.e., aged 20-39 yr) were considered sarcopenic. Subjects were further classified into 4 groups according to their obesity (i.e., body mass index > or =25 kg/m2) and sarcopenic status. Individuals' 10-yr CVD risk was determined using the Framingham risk model. The sarcopenic obese group had more participants (43.8% men, 14.6% women) with a high risk of CVD (> or =20%). The sarcopenic obese group was associated with an increased 10-yr CVD risk than the non-sarcopenic, non-obese group (odds ratio [OR], 2.49; 95% confidence interval [CI], 1.53-4.06, P<0.001 in men; OR, 1.87; 95% CI, 1.02-3.41, P=0.041 in women). Sarcopenic non-obese and non-sarcopenic obese subjects were not associated with an increased 10-yr CVD risk. Sarcopenic obesity, but not non-sarcopenic obesity, was closely associated with an increased CVD risk in Korean adults.
