A Case of "Full-house" Nephropathy in a Non-lupus Patient.
10.3339/jkspn.2014.18.2.128
- Author:
Ha Yeong YOO
1
;
Mikyung SON
;
Myung Hyun CHO
;
Byung Ok KWAK
;
Hye Won PARK
;
So Dug LIM
;
Sochung CHUNG
;
Kyo Sun KIM
Author Information
1. Department of Pediatrics, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea. 19890009@kuh.ac.kr
- Publication Type:Case Report
- Keywords:
Lupus nephritis;
Immunofluorescence;
Systemic lupus erythematosus;
Biopsy
- MeSH:
Antigen-Antibody Complex;
Autoantibodies;
Biopsy;
Child;
Fluorescent Antibody Technique;
Follow-Up Studies;
Hematuria;
Humans;
Lupus Erythematosus, Systemic;
Lupus Nephritis;
Male;
Prognosis;
Proteinuria;
Urinalysis
- From:Journal of the Korean Society of Pediatric Nephrology
2014;18(2):128-131
- CountryRepublic of Korea
- Language:English
-
Abstract:
Histopathologic evidence of "full-house" immune complex deposits is a pathognomonic feature of lupus nephritis. This report presents the case of a 12-year-old boy with persistent microscopic hematuria and proteinuria. He was diagnosed with "full-house" nephropathy based on a renal biopsy. However, there was no other clinical or biological evidence of systemic lupus erythematosus (SLE). Although the potential for isolated "full-house" nephropathy preceding SLE is unclear, such patients should be followed for clinical signs and autoantibodies of SLE. In most cases, microscopic hematuria has a good prognosis, and follow-up usually requires only regular urinalysis. However, we should be aware of isolated "full-house" nephropathy that remains asymptomatic for a long time, as few patients with no clinical signs and negative serology ultimately develop SLE.
