1 Case: Pulmonary Giant Cell Carcinoma.
- Author:
Hyun Goo KIM
1
;
Young Ho CHOI
;
Jae Joon HWANG
;
Oug Jin KIM
;
Hak Jae KIM
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Guro Hospital, Korea University.
- Publication Type:Case Report
- Keywords:
Carcinoma, bronchogenic;
Carcinoma, non-small cell lung;
Lung neoplasm
- MeSH:
Angioplasty;
Carcinoma, Bronchogenic;
Carcinoma, Giant Cell*;
Carcinoma, Large Cell;
Carcinoma, Non-Small-Cell Lung;
Chemotherapy, Adjuvant;
Coronary Vessels;
Emperipolesis;
Giant Cells*;
Hemoptysis;
Humans;
Lung Neoplasms;
Male;
Middle Aged;
Neoplasm Metastasis;
Neutrophils;
Radiotherapy;
Recurrence;
Thorax;
Tomography, X-Ray Computed
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
1999;32(2):185-188
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The pulmonary giant cell carcinoma is classified as a variant of a large cell carcinoma and is diagnosed by the minimum component of 10% huge, pleomorphic and multinucleated giant tumor cell and emperipolesis of the neutrophils into the tumor cells. This tumor is characterized by local recurrences and early metastasis with extremely short patient survival. However, there are some reports that state that the survival time was extended by the operative resection and postoperative adjuvant chemotherapy and radiotherapy. A 46-year old male was admitted with complaint of hemoptysis for 2 months. Through chest X-ray and chest CT, a 5cm sized mass was found in the apical segment of the right upper lobe. During the preoperative evaluation, stenotic lesion in the left anterior descending coronary artery was found and treated by percutaneous transarterial coronary angioplasty. Four weeks later, right upper lobectomy was performed and the mass was proven to be a giant cell carcinoma. The patient received adjuvant chemotherapy and radiotherapy.