A case of Ki-1 positive large-cell lymphoma.
- Author:
Chong Hyeok KIM
;
Seong Yeol LEE
;
Chil Hwan OH
- Publication Type:Original Article
- Keywords:
Ki-1 positive large-cell lymphoma;
monoclonal antibody Ki-l(CO30)
- MeSH:
Aged;
Humans;
Lymphocytes;
Lymphoma*;
Lymphoma, Large-Cell, Anaplastic;
Male;
Mediastinum;
Skin;
Ulcer
- From:Korean Journal of Dermatology
1993;31(3):444-448
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In 1985, Stein et al, indentified an anaplastic large-cell malignant lymphoma that was distinctive because of the diffuse dermal infiltration of pleomorphic large lymphocytes, sinus growth pattern, and reactivity with the monoclonal antibody Ki-1(CD30). The clinical feature; distinguishing anaplastic large-cell Ki-1 lymphoma include a young median age, frequent peripheral adenopathy with sparing of the mediastinum, and extranodal disease with skin the most common sitc of involvement. We report a case of Ki-1 postive large-cell lymphoma in a 74-year-old male patient who presented with multiple ulcerated nodules on the right shin area.