Experience of the Use of Three Screening Kits, Enzygnost Anti-HIV1/2 Plus, ABBOTT TESTPACK HIV- 1/HIV-2 & SERODIA. HIV- 1/2 for the Detection of Antibodies to HIV.
- Author:
Gyoung Yim HA
;
Eun Ha KOH
;
Moon Youn KIM
- Publication Type:Original Article
- MeSH:
Antibodies*;
Blood Donors;
Blotting, Western;
HIV Infections;
HIV*;
HIV-1;
HIV-2;
Humans;
Korea;
Mass Screening*;
Prevalence;
Sensitivity and Specificity
- From:Korean Journal of Blood Transfusion
1995;6(2):161-168
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We compared the performance of three screening kits for the detection of anti-HIV in 187 samples; Enzygnost Anti-HIV 1/2 Plus, ABBOTT TESTPACK HIV- 1/HIV-2 & SERODIA. HIV- 1/2. Four samples, 3 serums and 1 CSF, from 2 patients were repeatedly reactive in all three screening kits and 2 serum specimens were confirmed positive(HIV-1) by the western blot assay. The sensitivity and specificity of all three screening kits were 100% and 98.9%, respectively. In Korea, the cause of AIDS is mostly HIV-1 and the prevalence is very low. So, all three screening kits were useful for the detection of anti-HIV from patients and blood donors. But the use of screening kit for the detection of anti-HIV-1, anti-HIV-2 and anti-HIV-I subtype O will be needed for the decrement of false negative rate because HIV infection has been increased, especially, HIV-2 infection and pediatric AIDS patient by vertical transmission were also reported, currently.
