Changes in Rabbit Corneal Thickness During Radial Keratotomy.
- Author:
Sung Won LEE
1
;
Man Soo KIM
Author Information
1. Department of Ophthalmology, Catholic Medical College, Kananam St. Mary's Hospital, Seoul, Korea.
- Publication Type:Original Article
- MeSH:
Hot Temperature;
Keratotomy, Radial*;
Ultrasonics
- From:Journal of the Korean Ophthalmological Society
1987;28(2):299-305
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Corneal thickness is of paramount importance in radial keratotomy, The corneal thickness is usually measured before the surgery and it is used to set the length of knife blade for the surgery. But corneal thickness is not monitored during surgery. Some studies report the change of the corneal thickness during surgery and heat from the operating microscope and air current is considered as the factors which affect the corneal thickness during surgery. The purpose of this study is to determine the change in corneal thickness during radial keratotomy in rabbit. The corneal thickness was measured with ultrasonic pachymeter(Vida 55, U.S.A.). Forty-four rabbits(44 eyes) received radial keratotomy and the central corneal thickness was taken just before the operation and immediately, 1 day and 1 week after the operation. Seven rabbits(7 eyes) were served as control and they were exposed to the same operating conditions but no surgery was performed. The corneal thickness was measured at 0 minute, 5 minutes and 10 minutes respectively. The results were as follows: 1) The corneal thickness of the experimental group before the operation and immediately, 1 day and 1 week after the operation were 361.57 +/- 19.63 micrometer, 328.25 +/- 22.97 micrometer, 346.07 +/- 19.36 micrometer and 351.02 +/- 20.94 micrometer respectively. 2) The corneal thickness of the control group at 0 minute, 5 minutes and 10 minutes were 367.29 +/- 48.70 micrometer, 341.29 +/- 66.43 micrometer, and 320.43 +/- 74.20 micrometer respectively. 3) The corneal thickness of experimental group was reduced by 9.07% immediately after surgery than that before the operation, and it was significant statistically(p<0.000). 4) The corneal thickness of experimental group on 1 day and 1 week after operation was reduced by 4.18% and 2.85% than that before operation, and it was significant statistically (p<0.000 respectively). 5) In control group the corneal thickness of 5 minutes and 10 minutes was reduced by 7.60% and 13.54% than that of 0 minute, and it was significant statistically(P-value; 0.033, 0.009 respectively). 6) There was no statistically significant difference between the corneal thickness in experimental and control group at 5 minutes and 10 minutes respectively(p-value; 0.466, 0.816 respectively).