Pulmonary embolism in a healthy woman using the oral contraceptives containing desogestrel.
10.5468/ogs.2017.60.2.232
- Author:
Min Jeong PARK
1
;
Gyun Ho JEON
Author Information
1. Department of Obstetrics and Gynecology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea. jeon285@hotmail.com
- Publication Type:Case Report
- Keywords:
Contraceptives, oral, combined;
Desogestrel;
Pulmonary embolism
- MeSH:
Contraceptives, Oral*;
Contraceptives, Oral, Combined;
Desogestrel*;
Female;
Humans;
Progestins;
Pulmonary Embolism*;
Risk Factors;
Smoke;
Smoking;
Thrombosis;
Venous Thromboembolism;
Venous Thrombosis;
Young Adult
- From:Obstetrics & Gynecology Science
2017;60(2):232-235
- CountryRepublic of Korea
- Language:English
-
Abstract:
Venous thromboembolism is well known as one of the rare but serious adverse effects of combined oral contraceptives (COCs). The COCs with third and fourth generation progestogens were found to have higher risk of venous thrombosis than those with second generation progestogens. We present a case of pulmonary embolism in a 23-year-old nulligravid woman who was using COCs containing the third generation progestogen (desogestrel). At the time of presentation of the adverse effect, she had been using the COCs for 4 months. She had no additional risk factors for thrombosis such as smoking, surgery, tumor as well as genetic factors. This case demonstrates even young women in otherwise good health may be at risk of venous thromboembolism from low-dose formulations of COCs as an over-the-counter drug. We describe this case with a brief review of literatures.