Subretinal Hemorrhage After Photodynamic Therapy for Age-Related Macular Degeneration.
10.3341/jkos.2008.49.10.1603
- Author:
Jae Moon YOON
1
;
Ho Soong KIM
;
Jae Hoon KANG
;
Hee Sung YOON
Author Information
1. Sungmo Eye Hospital, Pusan, Korea. heesyoon@dreamwiz.com
- Publication Type:Original Article
- Keywords:
Age-Related Macular;
Degeneration;
Photodynamic Therapy;
Subretinal hemorrhage
- MeSH:
Angiography;
Eye;
Fluorescein Angiography;
Hemorrhage;
Humans;
Macular Degeneration;
Photochemotherapy;
Photography;
Retrospective Studies;
Triazenes;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2008;49(10):1603-1610
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the clinical features of subretinal hemorrhage after photodynamic therapy in eyes with exudative age-related macular degeneration. METHODS: We retrospectively reviewed data for 267 eyes of 243 patients who had undergone PDT for the treatment of ARMD between January 2005 and December 2006. Best corrected visual acuity, fundus photography, fluorescein angiography, and ICG angiography were performed before and after treatment. We followed up the patients at 1 week, 1 month, and 3 months after treatment and at 3-month intervals thereafter. RESULTS: Postoperative subretinal hemorrhage was seen in 36 (13.4%) of 267 eyes. The pretreatment and post-treatment mean visual acuities were logMAR 0.80 and logMAR 1.05 respectively, representing a decrease of 2.05 lines. On FAG, two eyes were predominantly classic, four eyes were minimally classic, and 30 eyes were occult. The laser irradiation spot size was under 3,000 micrometer in one case and from 3,000 micrometer to 5,000 micrometer in 19 cases and over 5,000 micrometer in 16 eyes. CONCLUSIONS: Subretinal hemorrhage after PDT for ARMD can be a common complication in patients who have been treated for larger irradiation spot sizes and for pigment epithelial detachment (PED), so doctors should be aware of the risk of serious hemorrhagic complications in such situations.
