Clinical and Histopathological Observations of Actinic Keratoses in Korea.
- Author:
Sung Nam CHANG
1
;
Soo Il CHUN
;
Soo Nam KIM
;
Baik Kee CHO
;
Jae Bok JUN
;
Nack In KIM
;
Kee Suck SUH
;
Kwang Hyun CHO
;
Soo Chan KIM
;
Jai Kyoung KOH
;
Bang Soon KIM
;
Seung Chul LEE
;
Young Ho WON
;
Jong Min KIM
Author Information
1. Department of Dermatology, Dr. Soo-Il Chun's Skin Clinic, Korea.
- Publication Type:Original Article
- Keywords:
Actinic keratosis
- MeSH:
Actins*;
Animals;
Carcinoma, Basal Cell;
Carcinoma, Squamous Cell;
Cheek;
Cryotherapy;
Female;
Fluorouracil;
Forehead;
Horns;
Humans;
Incidence;
Keratoacanthoma;
Keratosis, Actinic*;
Korea*;
Male;
Nose
- From:Korean Journal of Dermatology
1997;35(5):931-939
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Although actinic keratoses is the most common precancerous cutaneous lesion, there has been no clinical and histopathological study about actinic keratoses in Korea. OBJECTIVE: Our purpose was to carry out a clinical and histopathological study about actinic keratoses in Korea. METHODS: 158 patients, diagnosed with actinic keratoses from 1987 to 1995 in Korea, were analyzed clinically and histopathologically. RESULTS: 1. The ratio of males to females was 1:2.4 and the most frequent age groups were the 6th(29.1%) and 7th decade(33.5%). 2. The duration of the lesions was more than 1 year in most cases. 3. The most commonly involved sites were the face, in which the cheek, nose and forehead were the most common sites. 4. Clinically, the size of the lesions was less than 1cm in many cases(66.8%). The color was erythematous in 57.9%, brownish in 26.7%, and dark brownish in 15.3%. Crust and scale were noted in 28.7% and 25.2%, respectively. In 4% of patients, cutaneous horn also was noted. 5. Squamous cell carcinoma was associated with actinic keratoses in 5.7%, basal cell carcinoma in 3.2%, and keratoacanthoma in 1.3%. 6. Histopathologically, hypertrophic types of actinic keratoses were noted in 25.0%, atrophic types in 21.3%, hypertrophic and atrophic types in 18.1%, bowenoid types in 17.6%, acantholytic types in 13.3%, and pigmented types in 4.7%. 7. The most commonly used methods of treatment for actinic keratoses were cryotherapy, surgical excision, 5 FU ointment, and electrodesiccation with good effect. CONCLUSION: Actinic keratoses in Koreans was present on the face most commonly over 50 years of age. It showed a more frequent incidence in females than males. The clinical course of the lesions was chronic and the association with other cutaneous malignancies was noted to be less than 6%. The various histopathological types were noted, including hypertrophic, atrophic, hypertrophic and atrophic, bowenoid, acantholytic, and pigmented. The most commonly used methods of treatment. for actinic keratoses were cryotherapy, surgical excision, 5-FU ointment, and electrodesiccation.
