A Case of Diabetic Nephropathy without Microalbuminuria in Type 1 Diabetes.
- Author:
Na Young LEE
;
Im Jeong CHOI
;
Gil Hyun KIM
;
Jin Hwa JUNG
;
Sung Mi KIM
;
Mi Young JEON
- Publication Type:Original Article
- Keywords:
Type1 diabetes;
Diabetic nephropathy;
Microalbuminuria;
Albumin excretion rate
- MeSH:
Diabetes Complications;
Diabetic Nephropathies*;
Early Diagnosis;
Filtration;
Glomerular Filtration Rate;
Humans;
Hypertension;
Kidney Failure, Chronic;
Mortality;
Prevalence;
Proteinuria
- From:Journal of Korean Society of Pediatric Endocrinology
2004;9(2):199-203
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Diabetes is a rapidly increasing heath care problem all over the world due to increased prevalence during past decade. Diabetic nephropathy develops in 25-30% of patients with type 1 diabetes and is the leading cause of end stage renal disease. Diabetic nephropathy is characterized by persistent proteinuria, decline in renal function, hypertension and increased cardiovascular morbidity and mortality. Early detection of diabetic nephropathy risk is an important goal because early diagnosis and treatment prevent advanced renal damage and other diabetic complications. Increased urinary albumin excretion rate is widely accepted as the first clinical sign of diabetic nephropathy. However, reduced glomerular filtration or hypertension could be the first manifestation in some diabetic patients. We need improved markers and predictors of diabetic nephropathy risk. We report a case of diabetic nephropathy and decreased glomerular filtration rate (GFR) without microalbuminuria occcured in type 1 diabetic patient.
