Effect of Microwave Hyperthermia on Radiotherapy of Human Mailignant Tumors: An Analysis of Clinicl Response of 42 Patients.
- Author:
Sei Chul YOON
1
;
Yoon Kyung OHO
;
Hak Jun GIL
;
Su Mi CHUNG
;
Kyung Sub SHINN
;
Yong Whee BAHK
Author Information
1. Department of Radiology, Catholic University Medical College, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Microwave;
Hyperthermia;
Radiotherapy Malignant tumor;
Clinical response
- MeSH:
Adenocarcinoma;
Carcinoma, Squamous Cell;
Fever*;
Hot Temperature;
Humans*;
Hyperthermia, Induced;
Microwaves*;
Neoplasms, Unknown Primary;
Radiation, Ionizing;
Radiotherapy*;
Sarcoma, Myeloid
- From:Journal of the Korean Society for Therapeutic Radiology
1987;5(1):31-36
- CountryRepublic of Korea
- Language:English
-
Abstract:
Radiobiological and clinical evidences indicate that hyperthermia combined with ionizing radiation produces a significant improvement in therapeutic effect of cancer. In general, malignant cells are more sensitive to heat than normal cells in the heat range of 41~45degree C. We report the experiences obtained from 42 patients with advanced malignant neoplasms managed with 2,450 MHz microwave-induced local hyperthermia and ionizing radiation at the Department of Radiology, Kangnam St. Mary's Hospital, Catholic University Medical College. A clinical analysis of 42 thermoirradiated patients showed result of 11(26%), 15(36%), 11(26%) and 5(12%) patients with complete response (CR), partial response (PR), minor response (MR) and no response (NR), respectively. Histologically, there were 17 (40.2%) squamous cell carcinomas, 12(28.6%) adenocarcinomas and 6 (14.3%) miscellaneous cancers. Eleven patients with CR consisted of five squamous cell carcinomas, five adenocarcinomas, and one chloroma. Among 15 patients with PR were five squamous cell carcinomas, five adenocarcinomas, three unknown primary tumors, and one poorly differentiated, and miscellaneous tumor each.
