Deep Neck Infection due to Severe Neutropenia induced by Terbinafine in a Patient with Systemic Lupus Erythematosus.
- Author:
Jong Tae YANG
1
;
Young Shin CHO
;
Yoo Chul JOO
;
Dai Yong JANG
;
Jong O KIM
;
Hee Kwan KOH
Author Information
1. Division of Rheumatology, Department of Internal Medicine, College of Medicine, Chosun University, Gwangju, Korea. ionos@kornet.net
- Publication Type:Case Report
- Keywords:
Terbinafine;
Neutropenia;
Systemic Lupus Erythematosus
- MeSH:
Anti-Bacterial Agents;
Causality;
Female;
Granulocytes;
Humans;
Korea;
Lupus Erythematosus, Systemic*;
Neck*;
Neutropenia*;
Onychomycosis;
Tracheostomy
- From:The Journal of the Korean Rheumatism Association
2002;9(2):137-140
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Terbinafine, a fungicidal agent used for the treatment of onychomycosis, has been found to be safe and adverse effects are usually mild and transient. Neutropenia is a rare side effect of terbinafine. Terbinafine-induced neutropenia have been reported 7 cases worldwide and these patients had no predisposing factors that give rise to developing neutropenia. To date there has not been reported in Korea. We report a case of systemic lupus erythematosus of 47-yearold female patient who developed deep neck infection requiring intravenous antibiotics, tracheostomy, granulocyte colony-stimulating factor(G-CSF) to recover from terbinafine-induced neutropenia.
