Kaposi's Sarcoma in a Patient with Iatrogenic Cushing's Syndrome.
- Author:
Yoo Sang BAEK
1
;
Won Ung SHIN
;
Tae Seok OH
;
Soo Bin SON
;
Hae Jun SONG
;
Chil Hwan OH
Author Information
1. Department of Dermatology, College of Medicine, Korea University, Seoul, Korea. choh@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Iatrogenic Cushing's syndrome;
Kaposi's sarcoma
- MeSH:
Aged;
Autoimmune Diseases;
Cushing Syndrome;
Dermis;
Female;
Humans;
Immunosuppressive Agents;
Leg;
Sarcoma, Kaposi
- From:Korean Journal of Dermatology
2011;49(7):610-613
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Kaposi's sarcoma (KS) is a multifocal proliferative vascular tumor involving cutaneous and extra-cutaneous tissues. KS has been reported in patients treated with immunosuppressive agents for autoimmune diseases. However, KS has rarely been reported in patients with iatrogenic Cushing's syndrome. A 77-year-old woman was evaluated with multiple asymptomatic violaceous nodules and plaques on both lower legs. She had been diagnosed with iatrogenic Cushing's syndrome and had been treated with low-dose corticosteroid replacement therapy for >10 years. A histopathologic study showed extensive vascular proliferation in the dermis with spindle-shaped cells. Immunohistochemical staining for CD31, CD34, human herpesvirus (HHV)-8, and D2-40 was positive. We hereby report a case of KS in a patient with iatrogenic Cushing's syndrome.
