Colonic adenocarcinoma metastatic to the thyroid gland: a case report with immunohistochemical investigation.
10.3346/jkms.1999.14.4.455
- Author:
Chul Hwan KIM
1
;
Young Wook PARK
;
Alberto G AYALA
;
Jae Y RO
Author Information
1. Department of Pathology, Korea University Guro Hospital, Seoul.
- Publication Type:Case Report ; Review
- Keywords:
Adenocarcinoma;
Neoplasm metastasis;
Immunohistochemistry;
Thyroid gland
- MeSH:
Adenocarcinoma/secondary*;
Adenocarcinoma/radiography;
Aged;
Carcinoembryonic Antigen/analysis;
Carrier Proteins/analysis;
Case Report;
Colonic Neoplasms/pathology*;
Female;
Human;
Immunoenzyme Techniques;
Intermediate Filament Proteins/analysis;
Keratin/analysis;
Microfilament Proteins/analysis;
Thyroid Neoplasms/secondary*;
Thyroid Neoplasms/radiography;
Thyroid Nodule/radiography;
Thyroid Nodule/chemistry;
Tomography, X-Ray Computed;
Tumor Markers, Biological
- From:Journal of Korean Medical Science
1999;14(4):455-459
- CountryRepublic of Korea
- Language:English
-
Abstract:
Clinically evident metastases of carcinomas to the thyroid gland are rare, particularly from a colorectal primary tumor. We present a case of colonic adenocarcinoma metastatic to the thyroid gland with histopathologic and immunohistochemical findings. A 68-year-old woman with a history of Dukes' stage B colon carcinoma presented a mass in the thyroid gland. The tumor was confirmed to be metastatic adenocarcinoma from the colon. The immunohistochemical findings demonstrated positive staining for cytokeratin 20, low-molecular-weight cytokeratin, villin and carcinoembryonic antigen, but stains were negative for cytokeratin 7 and thyroglobulin.
