Intravenous contrast media application using cone-beam computed tomography in a rabbit model.
- Author:
Min Sung KIM
1
;
Bok Yeol KIM
;
Hwa Young CHOI
;
Yoon Joo CHOI
;
Song Hee OH
;
Ju Hee KANG
;
Sae Rom LEE
;
Ju Han KANG
;
Gyu Tae KIM
;
Yong Suk CHOI
;
Eui Hwan HWANG
Author Information
- Publication Type:Original Article
- Keywords: Cone-Beam Computed Tomography; Contrast Media; Soft Tissue; Radiography
- MeSH: Adipose Tissue; Administration, Intravenous; Anesthesia, General; Animals; Body Weight; Cone-Beam Computed Tomography*; Contrast Media*; Ear; Femoral Vein; Models, Animal; Multidetector Computed Tomography; Rabbits; Radiography; Salivary Glands; Veins
- From:Imaging Science in Dentistry 2015;45(1):31-39
- CountryRepublic of Korea
- Language:English
- Abstract: PURPOSE: This study was performed to evaluate the feasibility of visualizing soft tissue lesions and vascular structures using contrast-enhanced cone-beam computed tomography (CE-CBCT) after the intravenous administration of a contrast medium in an animal model. MATERIALS AND METHODS: CBCT was performed on six rabbits after a contrast medium was administered using an injection dose of 2 mL/kg body weight and an injection rate of 1 mL/s via the ear vein or femoral vein under general anesthesia. Artificial soft tissue lesions were created through the transplantation of autologous fatty tissue into the salivary gland. Volume rendering reconstruction, maximum intensity projection, and multiplanar reconstruction images were reconstructed and evaluated in order to visualize soft tissue contrast and vascular structures. RESULTS: The contrast enhancement of soft tissue was possible using all contrast medium injection parameters. An adequate contrast medium injection parameter for facilitating effective CE-CBCT was a 5-mL injection before exposure combined with a continuous 5-mL injection during scanning. Artificial soft tissue lesions were successfully created in the animals. The CE-CBCT images demonstrated adequate opacification of the soft tissues and vascular structures. CONCLUSION: Despite limited soft tissue resolution, the opacification of vascular structures was observed and artificial soft tissue lesions were visualized with sufficient contrast to the surrounding structures. The vascular structures and soft tissue lesions appeared well delineated in the CE-CBCT images, which was probably due to the superior spatial resolution of CE-CBCT compared to other techniques, such as multislice computed tomography.
