A Case of Primary Central Nervous System Lymphoma with Panhypopituitarism.
- Author:
Won Young KIM
1
;
Won KIM
;
Gyu Chong CHO
;
Jung Suck HONG
;
Mi Woo LEE
;
Sung Eun JANG
;
Se Hyun OH
;
Kyoung Soo LIM
Author Information
1. Department of Emergency Medicine, University of Ulsan College of Medicine, Asan Medical Center, Korea. wonpia@yahoo.co.kr
- Publication Type:Original Article
- Keywords:
Primary central nervous system lymphoma;
Panhypopituitarism
- MeSH:
Aged;
Axis, Cervical Vertebra;
Biopsy;
Brain;
Brain Neoplasms;
Central Nervous System*;
Diabetes Insipidus, Neurogenic;
Female;
Humans;
Hyponatremia;
Incidence;
Lymphoma*
- From:Journal of the Korean Society of Emergency Medicine
2001;12(4):536-540
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A primary central nervous system lymphoma(PCNSL) is defined as a lymphoma limited to the cranialspinal axis without systemic involvement. PCNSLs were formerly very rare, only 0.5~1.2% of all intracranial neoplasms, and were usually associated with acquired immuno-deficiency syndrome(AIDS) and other immuno-compromised states. Recently, there has been a clear rise in the incidence of this disease among normal individuals. We describe a 77-year-old female with hyponatremia who presented with a confused mental state. Computed tomography(CT) of the brain demonstrated a suprasellar mass with enhancement. We evaluated the basic hormonal studies and the magnetic resonance imaging(MRI). A ventricular biopsy was done, and the result was a diffuse, large, B-cell-type malignant lymphoma. She presented panhypopituitarism and partial central diabetes insipidus. She received chemotheraphy and was discharged in an improved condition. We report a case of panhypopituitarism due to PCNSL and give a review of the literature.
