A Case of Chronic Bullous Dermatosis of Childhood.
- Author:
Jeong Ki RHEE
;
Sung Bum KANG
;
Baik Kee CHO
;
Won HOUH
- Publication Type:Case Report
- Keywords:
Chronic bullous dermatosis of childhood;
Dapsone
- MeSH:
Biopsy;
Child;
Dapsone;
Eosinophils;
Extremities;
Female;
Humans;
Immunoglobulin A;
Immunoglobulin G;
Mucous Membrane;
Neutrophils;
Pelvis;
Skin;
Skin Diseases*;
Transcutaneous Electric Nerve Stimulation
- From:Korean Journal of Dermatology
1988;26(5):708-713
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of chronic bullous dermatosis of childhood occurring in a 8-year-old girl, who has multiple, pruritic, tense, vesicobullous eruptions on the both extremities and pelvic region without mucous membrane inuolvement. A skin biopsy revealed subepidermal vesicles infiltrated with many neutrophiles and a few eosinophiles. Direct immunofluorescent study of the perilesional skin demonstrated moderate intensity of linear IgA and to a lesser degree of IgG deposition at the dermoepidermal junction. The skin lesions responded dramatically to oral dapsone therapy, initially 4mg/kg, and taporing to 2mg/kg for 27 days.
