A Case of Vesicular Pemphigoid.
- Author:
Ho Joon KIM
;
In Chul CHOI
;
Jae Bok JUN
;
Sang Lip CHUNG
- Publication Type:Case Report
- Keywords:
Vesicular pemphigoid
- MeSH:
Adult;
Dapsone;
Female;
Humans;
Immunoglobulin G;
Neutrophils;
Pemphigoid, Bullous*;
Prednisolone;
Skin
- From:Korean Journal of Dermatology
1988;26(5):719-723
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report herein a case of vesicular pemphigoid in a 39 year-old female, who had 1 month history of multiple, pruritic vesicles with erythematous maeules on the whole body, especielly on the flexural surface. The histological findings showed subepidermal vesicle which contained many neutrophils. Direct immvnofluorescent study of perilesional skin revealed linear deposits of C along the dermoepidermal junction and indirect immunofluorescent study revealed linear deposits of immunoglobulin G and Cy along the dermoepidermal junction. Initially, dapsone was tried without any benefit but skin lesions were controlled by a combination therapy of prednisolone and cyclphosphamide.