Cardiovascular Effect of Lidocaine in Patients under Halothane , Enflurane and Diazepam Anesthesia.
10.4097/kjae.1993.26.2.293
- Author:
Bong Ho SHIN
1
;
Sang Hyun GWAK
;
Sung Su CHUNG
;
In Ho HA
Author Information
1. Department of Anesthesiology, Chonnam National University Medical School, College of Dentistry, Kwangju, Korea.
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
Anesthetics;
halothane;
enflurane;
diazepam;
local Anesthetics;
lidocaine;
Cardiovascular effect
- MeSH:
Anesthesia*;
Anesthesia, Intravenous;
Anesthetics;
Anesthetics, Local;
Blood Pressure;
Depression;
Diazepam*;
Electrolytes;
Enflurane*;
Halothane*;
Heart Rate;
Hemodynamics;
Humans;
Injections, Intravenous;
Intracranial Hypertension;
Lidocaine*;
Reflex
- From:Korean Journal of Anesthesiology
1993;26(2):293-298
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To evaluate the cardiovascular effect of lidocaine and serum electrolytes during inhalational or intravenous anesthesia, thirty-two healthy patients were randomly divided into three groups and measured systolic pressure, diastolic pressure, mean pressure, heart rate and serum K+ and Na+ level were measured at 30 sec, l, 3, 6, 12 minutes after intravenous injection of lidocaine(1.5 mg/kg) during halothane-N2O-O2 or enflurane-N2O-O2 or diazepam-N2O-O2 anesthesia. In all 3 groups, the values of hemodynamic and serum electrolytes were not changed by 2% lidocaine. These results indicate that intravenous injection of lidocaine(1.5 mg/kg) to prevent undesirable reflexes and to prevent intracranial hypertension is a safe method without depression of hemodynamics.
