Significance of High Density Lesion on Immediate follow-up CT scan after Intraarterial Thrombolysis for Acute Ischemic Stroke.
- Author:
Kyung Soo KANG
1
;
Byung Chul LEE
;
Hye Seung LEE
;
Ki Han KWON
Author Information
1. Department of Neurology Hallym University College of Medicine.
- Publication Type:Original Article
- MeSH:
Carotid Artery, Internal;
Catheterization;
Catheters;
Contrast Media;
Emergencies;
Follow-Up Studies*;
Hemorrhage;
Humans;
Intracranial Hemorrhages;
Middle Cerebral Artery;
Stroke*;
Thrombolytic Therapy;
Tomography, X-Ray Computed*;
Urokinase-Type Plasminogen Activator
- From:Journal of the Korean Neurological Association
1996;14(1):53-60
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Although intracranial hemorrhage is a dreadful complication of thrombolytic therapy in acute ischemic stroke, increased densities on immediate CT after intraarterial thrombolytic therapy in some cases, does not have any clinical deterioration and improve dramatically on follow-up CT. This unusual observation inspired us to determine the nature of the lesion of increased density on immediate CT finding, after intraarterial thrombolytic therapy. SUBJECTS AND RESULTS: Eight patients presenting with acute middle cerebral artery or internal carotid artery territory strokes were treated by emergency intraarterial urokinase with superselective catheterization. Fight of them had the areas of increased density in the territory sustaining the ischemic event on the immediate CT, performed within 30 minutes after thrombolytic therapy. Most lesions resolved definitely on follow-up scan within 48 hours of their detection. No cases were associated with clinical deterioration. CONCLUSION: As those lesions were cleared so fast without any clinical deterioration, the area of increased density should not necessarily be interpreted as hemorrhage alone. The density change on immediate CT after intraarterial thrombolysis partially attributable to extravasated pure contrast materials.
