A Case of Steroid Dependent Eosinophilic Gastroenteritis Presenting as a Huge Gastric Ulcer.
10.7704/kjhugr.2012.12.2.103
- Author:
Yeon Ji KIM
1
;
Woo Chul CHUNG
;
Yaeni KIM
;
Yoon Yung CHUNG
;
Kang Moon LEE
;
Chang Nyo PAIK
;
Hyung Min CHIN
;
Hyun Joo CHOI
Author Information
1. Department of Internal Medicine, The Catholic University of Korea, College of Medicine, Seoul, Korea. jwchulkr@yahoo.co.kr
- Publication Type:Case Report
- Keywords:
Eosinophilic gastroenteritis;
Gastric ulcer;
Immunosuppressive agents
- MeSH:
Abdominal Pain;
Azathioprine;
Biopsy;
Edema;
Endocarditis;
Enteritis;
Eosinophilia;
Eosinophils;
Gastric Stump;
Gastritis;
Gastroenteritis;
Gastrointestinal Tract;
Ileum;
Immunosuppressive Agents;
Pyloric Antrum;
Recurrence;
Steroids;
Stomach Neoplasms;
Stomach Ulcer;
Ulcer
- From:The Korean Journal of Helicobacter and Upper Gastrointestinal Research
2012;12(2):103-107
- CountryRepublic of Korea
- Language:English
-
Abstract:
Eosinophilic gastroenteritis is defined as primary eosinophilic infiltration of the gastrointestinal tract. Endoscopic findings of this disease entity are non-specific, and huge gastric ulceration as initial presentation is extremely rare. We experienced a case of eosinophilic gastroenteritis presenting with abdominal pain in a 38 year-old-woman. Deep and huge ulceration in gastric antrum and body looked like advanced gastric cancer. Surgical resection was performed and histopathological examination showed dense infiltration of eosinophil without malignant cells. 5 years after surgery, diffuse abdominal pain and generalized edema developed and computed tomography showed entire wall thickening of the gastrointestinal tract. Random mucosal biopsy of the remnant stomach and terminal ileum showed mucosal eosinophilic infiltrations. She was treated with steroids and azathioprine but experienced frequent relapses and was dependent on steroids to maintain remissions. After 3 years, she died from infective endocarditis due to the prolonged use of immunosuppressive agents.
