Long-term Results of Vision and Fundus Findings in X-linked Juvenile Retinoschisis.
- Author:
Jong Joo LEE
1
;
Jeong Hun KIM
;
Ho Kyung CHOUNG
;
Jang Won HEO
;
Seong Joon KIM
;
Young Suk YU
Author Information
1. Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. ysyu@snu.ac.kr
- Publication Type:Original Article
- Keywords:
Fundus findings;
Visual acuity;
X-linked juvenile retinoschisis
- MeSH:
Follow-Up Studies;
Humans;
Male;
Reflex;
Retinoschisis*;
Retrospective Studies;
Visual Acuity;
Vitreous Hemorrhage
- From:Journal of the Korean Ophthalmological Society
2007;48(7):911-918
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate long-term changes in visual acuity, fundus findings and complications in X-linked juvenile retinoschisis. METHODS: A retrospective chart review was conducted on 48 patients diagnosed with X-linked juvenile retinoschisis and followed for a minimum of 12 months. RESULTS: Forty-eight males (mean age 5.7 years) were followed for a mean of 6.3 years. The mean visual acuities were 0.14 at the initial and most recent examinations without significant change (p=0.67). Macular abnormalities were seen in all eyes. Macular lesions varied as follows: decreased foveal reflex (12.5%), typical foveal schisis (77.1%), atrophic change (5.2%), and macula-involving peripheral schisis (5.2%). When patients had different macular findings, the mean visual acuities were significantly different among groups (p< or =0.005), except those between the atrophic change group and the macula-involving peripheral schisis group. Peripheral schisis was detected in 66% of patients. The fundus findings were stationary during the follow-up period except in complicated cases with vitreous hemorrhage (15.6%). CONCLUSIONS: X-linked juvenile retinoschisis causes bilateral visual acuity loss, affecting maculae. In uncomplicated cases, changes in visual acuity and fundus findings were not significant during the follow-up period.