Results Following Transpupillary Thermotherapy for Choroidal Neovascularization.
- Author:
Jun Mo LEE
1
;
Ji Eun KEUM
;
Sung Chul LEE
Author Information
1. Department of Ophthalmology, Siloam Hospital, Seoul, Korea. eyejune@medigate.net
- Publication Type:Original Article
- Keywords:
Age-related macular degeneration;
Choroidal neovascularization;
Transpupillary thermotherapy
- MeSH:
Absorption;
Choroid*;
Choroidal Neovascularization*;
Fibrosis;
Humans;
Hyperthermia, Induced*;
Macular Degeneration;
Retrospective Studies;
Subretinal Fluid;
Tomography, Optical Coherence
- From:Journal of the Korean Ophthalmological Society
2007;48(7):919-924
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To determine whether transpupillary thermotherapy can achieve significant efficacy in maintaining vision without significant adverse effects when used to treat age-related macular degeneration associated with choroidal neovascularization. METHODS: Retrospective chart reviews were made for 33 eyes of 32 patients diagnosed with age-related macular degeneration, and who had received transpupillary thermotherapy due to the development of choroidal neovascularization. Transpupillary thermotherapy was performed 1.4 times on average. RESULTS: Three months after the final therapy, 6 eyes (18%) showed improved vision, 11 eyes (34%) showed no change in vision, and 16 eyes (48%) showed worsening of vision. Of the 21 eyes of 21 patients who were available for optical coherence tomography before and after transpupillary thermotherapy, 19 eyes (90.5%) showed reduced macula thickness, and fundus photographs taken during the latest hospital visit revealed 11 eyes showing fibrosis. CONCLUSIONS: Although it negatively influences subretinal fluid absorption, transpupillary thermotherapy is effective in stabilizing choroidal neovascularization and improving visual accuracy in a short period of time. Thus, further study is warranted.