Primary Angiitis of the Central Nervous System Diagnosed by High-Resolution Vessel Wall MRI.
- Author:
Eun Bin CHO
1
;
Suk Jae KIM
;
Jihoon CHA
;
Tae Ok SON
;
Jun Pyo KIM
;
Oh Young BANG
;
Geyong Moon KIM
;
Chin Sang CHUNG
;
Kwang Ho LEE
Author Information
1. Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. sukjae.kim@gmail.com
- Publication Type:Case Report
- Keywords:
PACNS;
Vessel-wall MRI;
Therapeutic monitoring
- MeSH:
Adult;
Aphasia;
Azathioprine;
Brain;
Central Nervous System*;
Cerebrospinal Fluid;
Female;
Follow-Up Studies;
Headache;
Humans;
Magnetic Resonance Imaging*;
Meningitis, Aseptic;
Spinal Cord;
Vasculitis*;
Vasculitis, Central Nervous System
- From:Journal of the Korean Neurological Association
2013;31(4):262-265
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary angiitis of the central nervous system (PACNS) is a poorly understood form of vascular inflammatory disease that is restricted to the brain and spinal cord. A 38-year-old woman presented with severe headache and transient aphasia. Her cerebrospinal fluid exhibited aseptic meningitis, and high-resolution vessel-wall MRI (HRVW-MRI) revealed narrowing of multiple intracranial vessels with concentric wall thickening and diffuse enhancement, suggestive of PACNS. High-dose steroid and azathioprine therapy resulted in a significant improvement in vessel wall thickening, and enhancement was observed on the follow-up HRVW-MRI.
